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Administration of a 5 -reductase-2 inhibitor, finasteride, in rats 51 , 52 and monkeys 53 impairs male sexual differentiation and prostate development

Dose 2.4 mg = 0.96 ml = 96 IU on the insulin syringe

Major medical institutions including Cedars-Sinai, California Pharmacists Association, and California Hospital Association have also requested changes to the proposed regulations

The evidence has been largely RNA- and protein-based with increased concentrations of interleukin (IL)-4, tumor necrosis factor (TNF)- , soluble TNF receptor 1 (sTNFR1), and soluble IL-2 receptor consistently reported in BD compared to healthy controls [67, 68]

They are framed conservatively for research use, not as a clinical clearance