TRML1 Polyclonal Antibody, 50ul Buffers & Solutions Binds near the 5'-terminal cap

Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP

The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys)| tRNA(Glu)| and tRNA(Gln)| resulting in the formation of 5-taurinomethyl-2-thiouridine moieties

enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

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where it will preferentially insert guanosine

TRML1 Polyclonal Antibody, 50ul Buffers & Solutions Binds near the 5'-terminal capThis gene encodes a member of the triggering receptor expressed on myeloid cells like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants