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TRIUMPH-4: Metabolic findings beyond weight TRIUMPH-4 also produced two metabolic findings that are relevant beyond weight loss itself

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist drug

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GLP-1 and GIP receptors are G-protein-coupled receptors expressed primarily in pancreatic beta cells, the hypothalamus, and the GI tract