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Caspases can serve different roles in the apoptotic cascade: some act as initiators (e.g., caspase-8, caspase-9), while others function as effectors (e.g., caspase-3, -6, -7), ultimately executing apoptosis by cleaving essential cellular proteins [159]

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3D structures At the structural level, GSTs consist of an N-terminal domain adopting a thioredoxin fold and an all-helical C-terminal domain (Atkinson and Babbitt, 1971

Therefore, vaccination can be one of the most promising treatments for RA

The peptide functions as a geroprotective agent with profound effects on cellular aging, circadian rhythm regulation, and systemic rejuvenation