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Medical Classification: Class 1 Medicine Efficacy: Contains Tranexamic Acid, effective in improving dark spots (limited to melasma)

These results far exceed what is typically achieved through lifestyle modification alone, where sustained weight loss often falls in the 5 to 10% range even with intensive intervention

The viscosity is preferably lower than 500 cP, more preferably lower than 400 cP

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The simplified 2D microenvironmentdevoid of a 3D matrix, vasculature, and key factors such as CPfurther leads to dysregulated copper transporter expression and non-physiological toxicity responses [252]

The supernatants were collected for further protein quantification using BCA protein assay kit after centrifugation at 12,000 g at 4C for 15 minutes