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It is not evident whether these beneficial effects of GLP-1 agonists are secondary to weight loss or due to direct cardiac actions

However, when the physiological demand for antioxidants surpasses their bioavailability, the brain enters a state of REDOX imbalance in which ROS accumulate, leading to neuronal damage [6, 7]

Semaglutide, a GLP-1 receptor agonist, effectively lowers blood glucose levels, supports weight management reduces major cardiovascular events, decreases postprandial inflammation (PMID: 32910488, PMID: 32910487, PMID: 33068776 )