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Kuitunen (2024) systematically reviewed two register-based cohorts encompassing 938 pregnancies and similarly found no association between GLP-1 RA exposure and CA, though sample sizes were small and confidence intervals wide

Retatrutide demonstrated 24.2% body weight reduction in Phase 2 trials, approaching bariatric surgery outcomes

February 16, 2025 9:59 View More Debunking Myths About GLP-1 Medications: A Comprehensive Guide In this episode of our podcast, we delve into the fascinating world of GLP-1 medications, exploring their benefits, mechanisms,

Location: Indianapolis, IndianaWarning Letter Date: September 9, 2025FDA Department Issuing Warning: Center for Drug Evaluation and Research (CDER)Type of Warning: False & Misleading Claims/Misbranded DrugsSubject of Violation: An Oprah Special: Shame, Blame, and the Weight Loss Revolution, regarding Zepbound (tirzepatide) and Mounjaro (tirzepatide)FDA Warning: In the program, which aired on television in 2024 and until recently was available continuously on the ABC website and through various streaming services, Eli Lilly promoted Mounjaro and Zepbound in a manner that failed to present the serious risks of these drug products in a truthful and nonmisleading manner, despite FDAs prior correspondence (advisory comments dated June 13, 2022 and June 21, 2022)

This also supports the finding that the cardiovascular benefits are not restricted to those agents structurally similar to human GLP-1 but are more likely a class effect that is seen in all GLP-1RAs

Prescribing of AOM tirzepatide (brand name Zepbound) was observed in the first month of availability in pharmacies, December 2023