Cdc25C(Phospho Thr48) Polyclonal Antibody, 100ul Low-speed Centrifuges Mutations in TEAD1 cause Sveinsson's

Mutations in TEAD1 cause Sveinsson's chorioretinal atrophy

and inhibiting its expression partially suppresses p53-induced apoptosis

which catalyze the hydrolysis of GTP to GDP

This gene encodes a member of the suppressor of hairless protein family

Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160)

Cdc25C(Phospho Thr48) Polyclonal Antibody, 100ul Low-speed Centrifuges Mutations in TEAD1 cause Sveinsson'sThis gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B bound CDC2 and triggers entry into mitosis. It also suppresses p53 induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described.