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Insert the needle at a 45-90 degree angle (90 degrees for areas with more subcutaneous fat, 45 degrees for leaner areas)

ROS cause electrical (by altering the activity of various cellular currents and Ca 2+ -handling), structural (myocyte necrosis, apoptosis, myolysis and interstitial fibrosis that impair impulse propagation) and autonomic nervous system (further altering cellular electrophysiology) remodeling

doi:10.1111/nhs.12898

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FIGURE 7 Discussion The contribution of oxidative metabolism of AQ to cytotoxicity has previously been demonstrated by several studies (Naisbitt et al., 1998