CRISPR Editing Tool Box Catalog No.:LI30010-2S MM-102 specifically reduces expression of

MM-102 specifically reduces expression of two critical MLL1 target genes (HoxA9 and Meis-1)

including the premature-aging disease Hutchinson-Gilford progeria syndrome (HGPS)

4-tetrahydroquinolin-5-yl)methyl)amino)phenyl)propanoic acid

Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935)

a multitargeted inhibitor of histone deacetylase

CRISPR Editing Tool Box Catalog No.:LI30010-2S MM-102 specifically reduces expression ofProduct Information A very useful small molecule collection to improve CRISPR editing efficacy, 2 mg solid each for the following compounds: SCR7: a NHEJ inhibitor promotes the efficiency of HDR 45 fold for CRISPR editing in both human and mouse cell lines. RS 1: a RAD51 Stimulatory compound enhances CRISPR Cas9 and TALEN mediated knock in efficiency. (Z) 4 Hydroxytamoxifen: a previously characterised as an Estrogen Receptor antagonist and now found