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If you're planning to conceive, discuss discontinuing GLP-1 therapy with your healthcare provider beforehand

FOXO are transcription factors important in wound healing, and can either be activated by direct cysteine oxidisation, or in response to upstream redox signalling 143

Tak Y et al

Another consideration to make when using this approach is the potential aversive effects of manipulating ARC AgRP/NPY neuronal activity

BPC-157 should be considered investigational

"We don't really know why some people only lose 5% where some people are super responders and losing 30% of their body weight." Kushner thinks of the result as a kind of new settling point the medication helps establish, though why it lands so much lower for some people isn't well understood

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