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DARPins can selectively bind any given target protein with high affinity 30 , and HSA can be specifically targeted by albumin-binding DARPin too

The sugar cravings practically turned off

Preclinical study in mice with streptozotocin-induced diabetes that showed glucose-independent amelioration of kidney fibrosis with the DPP-4 inhibitor linagliptin

Diabetes Care 27, 19151921

Nevertheless, a great deal of work has yet to be carried out before our understanding of this important hormonereceptor interaction is complete and before the use of non-peptidic therapeutics becomes a reality