BX-912 535ye 993 whereas the MTD of docetaxel

whereas the MTD of docetaxel combined with MS-209 greatly reduced MCF-7/ADM tumor growth

MG149 is a potent and selective inhibitor of the MYST family (Tip60 and MOZ) of histone acetyltransferase (HAT)

Molecular Weight: 168

3-dihydro-7H-[1

Smiles: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)/C(=N\OCOCCOC)/[C@H](C)[C@@H](O)[C@]1(C)O

BX-912 535ye 993 whereas the MTD of docetaxelBX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. BX912 blocks PDK1 Akt signaling in tumor cells and suppresses the anchorage dependent growth of a variety of tumor cell lines (such as PC 3 cells) in culture or induces apoptosis. Product information CAS Number: 702674 56 4 Molecular Weight: 471. 35 Formula: C20H23BrN8O Chemical Name: N {3 [(5 bromo 4 {[2 (1H imidazol 5 yl)ethyl]amino}pyrimidin 2 yl)amino]phenyl}pyrrolidine 1 carboxamide