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10.1074/jbc.M406185200 [DOI] [PubMed] [Google Scholar] 16.Scanlan MJ, Raj BK, Calvo B, Garin-Chesa P, Sanz-Moncasi MP, Healey JH, et al

Brain imaging studies, biomarker tracking, and cognitive assessments must be conducted over extended periods to confirm lasting impact

1,5 Additional long-term randomized controlled trials are needed to clarify optimal dosing strategies, long-term safety, and the extent to which gut microbiota alterations contribute to konjac's metabolic effects

Because bones adapt to the weight they carry, losing weight means less stress on the skeleton, and over time this can lead to small decreases in bone strength

Tirzepatide can and should continue long-term, but phentermine should be viewed as a temporary addition rather than a permanent part of the protocol

Complications of type 2 diabetes