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HEXI2 Polyclonal Antibody, 50ul PCR Series Mutations in this gene and/or

SKU: 59140977852

4.1
USD162.00 USD209.00

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HEXI2 Polyclonal Antibody, 50ul PCR Series Mutations in this gene and/orThis gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin dependent kinase P TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing

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Description

Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia

Mutations in EIF2AK3 are associated with Wolcott-Rallison syndrome

The protein is able to form a dimer stabilized by noncovalent forces

BNIP2 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family

around which approximately 146 bp of DNA is wrapped in repeating units

HEXI2 Polyclonal Antibody, 50ul PCR Series Mutations in this gene and/orThis gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin dependent kinase P TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing

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