PTEN(Phospho Ser385) Polyclonal Antibody, 50ul Deep Well Plates The protein localizes to the

The protein localizes to the nucleolus during interphase and to the chromosomes during M phase

specifically the B-type cyclins

This gene has abundant and specific expression in the kidney

Low BMD is a risk factor for osteoporotic fracture

This protein also plays a role in synapse organization between parallel fibers and Purkinje cells

PTEN(Phospho Ser385) Polyclonal Antibody, 50ul Deep Well Plates The protein localizes to theThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide