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HoxD3 Polyclonal Antibody, 50ul Thermo Mix An important paralog of POU3F1

SKU: 10589108035

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HoxD3 Polyclonal Antibody, 50ul Thermo Mix An important paralog of POU3F1HOXD3 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31 2q37 chromosome regions.

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Description

An important paralog of POU3F1 is POU6F1

Alternatively splicing results in multiple transcript variants

that controls survival and differentiation of mammalian neurons

Members of this family encode proteins containing a homeobox homology domain| proline rich region and Src-homology 3 (SH3) domain| and are components of the Abi/WAVE complex which regulates actin polymerization

and effectors

HoxD3 Polyclonal Antibody, 50ul Thermo Mix An important paralog of POU3F1HOXD3 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31 2q37 chromosome regions.

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