GPR114 Polyclonal Antibody, 20ul Bottles Mice lacking the homolog gene

Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype

Two transcript variants encoding different isoforms have been found for NOTCH2

The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors

Three transcript variants have been identified for this gene

rheumatoid arthritis

GPR114 Polyclonal Antibody, 20ul Bottles Mice lacking the homolog geneADGRG5 encodes a member of the adhesion family of G protein coupled receptors. Members of this family are characterized by long N termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants.