TGIF2 Polyclonal Antibody, 100ul Cryopreservation ACVR1B encodes an activin A

ACVR1B encodes an activin A type IB receptor

Its expression is up-regulated in some types of cancer

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus

which has a greater tendency to allow potassium to flow into a cell rather than out of a cell

thereby negatively regulating the activity of the DDX58 gene product

TGIF2 Polyclonal Antibody, 100ul Cryopreservation ACVR1B encodes an activin AThe protein encoded by this gene is a DNA binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta responsive genes. This gene is amplified and over expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read through transcription also exists between this gene and the