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Fe65L Polyclonal Antibody, 100ul Immune Repertoire Sequencing The MAF bZIP transcription factor

SKU: 11430619667

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Fe65L Polyclonal Antibody, 100ul Immune Repertoire Sequencing The MAF bZIP transcription factorThe amyloid beta precursor protein binding family B member 2 encoded by APBB2 interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript

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Description

The MAF bZIP transcription factor F encoded by MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain

Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined

including stimulation of DNA repair

Coexpression and binding of these partners initiates profound morphological changes

Mutations in this gene have been associated with KBG syndrome| which is characterized by macrodontia| distinctive craniofacial features| short stature| skeletal anomalies| global developmental delay| seizures and intellectual disability

Fe65L Polyclonal Antibody, 100ul Immune Repertoire Sequencing The MAF bZIP transcription factorThe amyloid beta precursor protein binding family B member 2 encoded by APBB2 interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript

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