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FIBA Polyclonal Antibody, 100ul Pasteur Pipets It is also involved in

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FIBA Polyclonal Antibody, 100ul Pasteur Pipets It is also involved inThis gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants,

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Description

It is also involved in the maintenance of chromatin structure| the regulation of gene expression| and the stress response

This gene lies in close proximity to thymidylate synthase gene on chromosome 18

The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy

FIBA Polyclonal Antibody, 100ul Pasteur Pipets It is also involved inThis gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants,

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