SNX7 Rabbit Polyclonal Antibody, 50ul Cell Function Analysis Homeodomain-interacting protein kinase 4 lacks

Homeodomain-interacting protein kinase 4 lacks a nuclear localization signal and a C-terminal autoinhibitory domain

2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits

This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand

Moderate expression in heart and liver| low expression in skeletal muscle| kidney and testis

The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways

SNX7 Rabbit Polyclonal Antibody, 50ul Cell Function Analysis Homeodomain-interacting protein kinase 4 lacksThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain which is a phosphoinositide binding domain and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.