Phospho-Akt2 (S474) Polyclonal Antibody, 20ul Gel & Buffers The Hippo pathway is an

The Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release

designed to push you to new heights

Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma

CDH15 is a member of the cadherin superfamily of genes

Phospho-Akt2 (S474) Polyclonal Antibody, 20ul Gel & Buffers The Hippo pathway is anAKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine threonine kinases containing SH2 like (Src homology 2 like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT serine threonine kinase 2 is a general protein kinase capable of