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HESX1 Polyclonal Antibody, 50ul NGS Oligos The protein encoded by APBA3

SKU: 12103926680

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HESX1 Polyclonal Antibody, 50ul NGS Oligos The protein encoded by APBA3This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1 related growth hormone deficiency, and combined pituitary hormone deficiency.

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Description

The protein encoded by APBA3 (amyloid beta precursor protein binding family A member 3) is a member of the X11 protein family

An important paralog of this gene is HSFX1

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where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction

leading to activate transcription of the beta-globin locus (By similarity)

HESX1 Polyclonal Antibody, 50ul NGS Oligos The protein encoded by APBA3This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1 related growth hormone deficiency, and combined pituitary hormone deficiency.

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