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Stat3(Phospho-Ser754) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies Members of the connecdenn family|

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Stat3(Phospho-Ser754) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies Members of the connecdenn family|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.

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Description

Members of the connecdenn family| such as DENND1A| function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins

Mutations in this gene have been associated with late-onset retinal degeneration

EMR4P is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration

and heat-labile enterotoxins of E

Stat3(Phospho-Ser754) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies Members of the connecdenn family|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.

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