OTOGL Rabbit Polyclonal Antibody, 20ul Bottle-Top Dispenser The encoded protein mediates platelet

The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation

Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity

with some of them functioning as activators and some as repressors of transcription

Three transcript variants encoding three different isoforms have been found for this gene

The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular

OTOGL Rabbit Polyclonal Antibody, 20ul Bottle-Top Dispenser The encoded protein mediates plateletThe protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness.