APBB3 Rabbit Polyclonal Antibody, 20ul Electrophoresis & Labeling This gene encodes the alpha-1D

This gene encodes the alpha-1D subunit

This protein associates with the embryonic ectoderm development protein

The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta)

Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome

This gene may be involved in coronary artery disease and in the pathogenesis of sepsis

APBB3 Rabbit Polyclonal Antibody, 20ul Electrophoresis & Labeling This gene encodes the alpha-1DThe protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta amyloid precursor protein (APP) as well as to other APP like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.