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CO9A2 Polyclonal Antibody, 100ul Filtration Three different versions of extraskeletal

SKU: 13337357066

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CO9A2 Polyclonal Antibody, 100ul Filtration Three different versions of extraskeletalThis gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia.

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Description

Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes

The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation| apoptosis| differentiation| the stress response| and regulation of immune genes

which endow host cells with specific biological characteristics

such as GPR176

The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes

CO9A2 Polyclonal Antibody, 100ul Filtration Three different versions of extraskeletalThis gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia.

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