IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents This gene maps in a

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

Amplification and overexpression of this gene have been observed in several types of human carcinomas

This gene encodes a protein with similarity to members of the myosin light chain kinase family

tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family

IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents This gene maps in aIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants