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MARH8 Polyclonal Antibody, 20ul Electrophoresis & Labeling and as a positive regulator

SKU: 13694112092

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MARH8 Polyclonal Antibody, 20ul Electrophoresis & Labeling and as a positive regulatorMARCH8 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003

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Description

and as a positive regulator by preventing the processing of GLI3 into its repressor form

The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis

HLA-DOB belongs to the HLA class II beta chain paralogues

The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions

PRL encodes the anterior pituitary hormone prolactin

MARH8 Polyclonal Antibody, 20ul Electrophoresis & Labeling and as a positive regulatorMARCH8 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003

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