SPAK(Phospho Ser323) Polyclonal Antibody, 20ul Cell Culture & Maintenance Elastase 3B preferentially cleaves proteins

Elastase 3B preferentially cleaves proteins after alanine residues

forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP)

Interacts with 14-3-3 family members in a phosphorylation-dependent manner

This protein may be involved in organizing the centrosome during interphase and mitosis

The protein encoded by this gene is a member of the CRK-associated substrates family

SPAK(Phospho Ser323) Polyclonal Antibody, 20ul Cell Culture & Maintenance Elastase 3B preferentially cleaves proteinsThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the