DHB1 Polyclonal Antibody, 50ul Fluorescent Staining and has been found to

and has been found to be overexpressed in 10% of clear cell renal carcinomas

Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms

The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains

These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart

A pseudogene of this gene has been identified on chromosome X

DHB1 Polyclonal Antibody, 50ul Fluorescent Staining and has been found toThis gene encodes a member of the 17beta hydroxysteroid dehydrogenase family of short chain dehydrogenases reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4 androstenedione,