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ORCTL2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management and its alternative splicing generates

SKU: 14175126128

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ORCTL2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management and its alternative splicing generatesSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been

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Description

and its alternative splicing generates 3 transcript variants

The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly

These proteins function either as transcriptional activators or repressors of numerous genes

Designed with a flat cap and conical bottom

ranging from neonatal adrenoleukodystrophy to Zellweger syndrome

ORCTL2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management and its alternative splicing generatesSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been

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