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GRK2(Phospho-Tyr86) Polyclonal Antibody, 20ul Palm Micro Centrifuges This gene encodes a subunit

GRK2(Phospho-Tyr86) Polyclonal Antibody, 20ul Palm Micro Centrifuges This gene encodes a subunit

Name: GRK2(Phospho-Tyr86) Polyclonal Antibody, 20ul Palm Micro Centrifuges This gene encodes a subunit
Brand: clickpoint.com.au
SKU: 14209656230
Price: 97.20 USD
Availability: InStock
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SKU: 14209656230

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GRK2(Phospho-Tyr86) Polyclonal Antibody, 20ul Palm Micro Centrifuges This gene encodes a subunitThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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Description

This gene encodes a subunit of the integrator complex

see MIM 114085

also known as HP43

Expression of this gene is up-regulated in some types of cancer

Mutations in this gene are associated with X-linked Alport syndrome

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