USP15 Polyclonal Antibody, 50ul Cellular Function Assays Dentatorubral pallidoluysian atrophy (DRPLA) is

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia

The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain

disease:Defects in OSMR are the cause of amyloidosis type 9 (AMYL9)

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential

The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase

USP15 Polyclonal Antibody, 50ul Cellular Function Assays Dentatorubral pallidoluysian atrophy (DRPLA) isUSP15 (ubiquitin specific peptidase 15) encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor