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PKC delta(Phospho Thr507) Polyclonal Antibody, 100ul Vortex Mixer HLA-DOA belongs to the HLA

SKU: 14560034251

4.7
EUR123.75 EUR153.75

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PKC delta(Phospho Thr507) Polyclonal Antibody, 100ul Vortex Mixer HLA-DOA belongs to the HLAProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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Description

HLA-DOA belongs to the HLA class II alpha chain paralogues

The enzyme plays a role in several pathophysiological processes including hemostasis

RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells

Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094)

subcellular location:Expressed diffusely throughout the nucleus

PKC delta(Phospho Thr507) Polyclonal Antibody, 100ul Vortex Mixer HLA-DOA belongs to the HLAProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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