Bovine Myeloid Differentiation Primary Response Protein Myd88, MYD88 ELISA Kit , 96T Bacterial Expression This gene is localized in

This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies

The type I cytokeratins are clustered in a region of chromosome 17q12-q21

which is located on the X chromosome

Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease

EphA7 (Hek11/MDK1)

Bovine Myeloid Differentiation Primary Response Protein Myd88, MYD88 ELISA Kit , 96T Bacterial Expression This gene is localized inAdapter protein involved in the Toll like receptor and IL 1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2 and TRAF6, leading to NF kappa B activation, cytokine secretion and the inflammatory response. Increases IL 8 transcription. Involved in IL 18 mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN beta, NOS2 INOS, and IL12A genes