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Fli-1 Polyclonal Antibody, 50ul Protein Modification and upregulated in a breast

SKU: 15745677792

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PLN162.00 PLN192.00

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Fli-1 Polyclonal Antibody, 50ul Protein Modification and upregulated in a breastFLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA binding domain. FLI1 can undergo a t (11; 22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia associated t (4; 11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple

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Description

and upregulated in a breast cancer cell line after estrogen treatment

The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions

Its depletion enhances the cytotoxic action of the chemotherapeutic drugs

similar to Vps4 protein in yeast

The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix

Fli-1 Polyclonal Antibody, 50ul Protein Modification and upregulated in a breastFLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA binding domain. FLI1 can undergo a t (11; 22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia associated t (4; 11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple

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