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Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases The protein may also play

SKU: 16372223438

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Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases The protein may also playThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have

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Description

The protein may also play a role in the morphological organization of liver and intestine

Multiple transcript variants encoding different isoforms have been found for NR4A1

Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity

It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency

a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators

Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases The protein may also playThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have

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