PKR(Phospho Thr451) Polyclonal Antibody, 50ul Protein Post-translational Modification The encoded protein mediates platelet

The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation

With a lightning fast reaction rate of 1 rxn/μl and 30 rxns per kit

It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets

The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice

• Two programs P1/P2

PKR(Phospho Thr451) Polyclonal Antibody, 50ul Protein Post-translational Modification The encoded protein mediates plateletThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.