Akt1/3 Polyclonal Antibody, 100ul Custom RNA Oligos The protein encoded by CCNE1

The protein encoded by CCNE1 (cyclin E1)belongs to the highly conserved cyclin family

This gene encodes a member of the F-box protein family| which is characterized by an approximately 40 amino acid motif| the F-box

The product of HSF1 is a heat-shock transcription factor

in the N-terminal domain (summary by Teglund et al

Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame

Akt1/3 Polyclonal Antibody, 100ul Custom RNA Oligos The protein encoded by CCNE1The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a