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Hrs Polyclonal Antibody, 100ul[BT-AP04217] Centrifuge Tube (Bottle) The gene product is secreted

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Hrs Polyclonal Antibody, 100ul[BT-AP04217] Centrifuge Tube (Bottle) The gene product is secretedThe protein encoded by HGS (hepatocyte growth factor regulated tyrosine kinase substrate) regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.

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Description

The gene product is secreted and further processed to make the biologically active form

one of which contains a clathrin-mediated trans-Golgi signal and an endoplasmic reticulum exit signal

and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy

This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4

This gene encodes a member of a family of inositol polyphosphate-5-phosphatases

Hrs Polyclonal Antibody, 100ul[BT-AP04217] Centrifuge Tube (Bottle) The gene product is secretedThe protein encoded by HGS (hepatocyte growth factor regulated tyrosine kinase substrate) regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.

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