RB6I2 Polyclonal Antibody, 100ul Insect Expression Dok-5 and Dok-6 are more

Dok-5 and Dok-6 are more similar to each other than to the other Dok family members

The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes

The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1)

Contains 2 Calx-beta domains

Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation

RB6I2 Polyclonal Antibody, 100ul Insect Expression Dok-5 and Dok-6 are moreThe protein encoded by this gene is a member of a family of RIM binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10; 12)(q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.