PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody, 50ul Pipette Controller The NPLOC4-UFD1L-VCP complex regulates spindle

The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope

which is thought to be an exon splice enhancer

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain

A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified| but it is thought to be non-coding

Alternatively spliced transcript variants have been found for ELOVL5

PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody, 50ul Pipette Controller The NPLOC4-UFD1L-VCP complex regulates spindleThe protein encoded by this gene catalyzes the formation of inositol 1 4 5 trisphosphate and diacylglycerol from phosphatidylinositol 4 5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example when activated by SRC the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi where it