OAT1 Polyclonal Antibody, 50ul[BT-AP12159] Peripheral Blood Separation Tube Mutations in this gene are

Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10)

Alternatively spliced transcript variants encoding distinct isoforms have been reported

and mutations in this gene have been associated with different neuromuscular diseases

interaction with estrogen receptors has been demonstrated

Expression of this gene is repressed by phsphorylation

OAT1 Polyclonal Antibody, 50ul[BT-AP12159] Peripheral Blood Separation Tube Mutations in this gene areMultiple cysteine residues are necessary for proper targeting to the plasma membrane.,Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium independent uptake of 2,3 dimercapto 1 propanesulfonic acid (DMPS) (By