Laminin Gamma-3 Polyclonal Antibody, 20ul Nucleic Acid Amplification and mutations in SCNN1B have

and mutations in SCNN1B have been associated with pseudohypoaldosteronism type 1 (PHA1)

so named for the LIM domains they contain

Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis

Dare to push the boundaries

like other members of the family

Laminin Gamma-3 Polyclonal Antibody, 20ul Nucleic Acid Amplification and mutations in SCNN1B haveLaminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of