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PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing systemic lupus erythematosus and sarcoidosis

SKU: 18326374942

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PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing systemic lupus erythematosus and sarcoidosisThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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Description

systemic lupus erythematosus and sarcoidosis

a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex

Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment| and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters

The RefSeq Project has decided to create four representative RefSeq records

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules

PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing systemic lupus erythematosus and sarcoidosisThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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