IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 50ul Nucleic Acid Extraction Mutations in this gene have

Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia

There is a pseudogene for this gene on chromosome 1

UBE4B encodes an additional conjugation factor

including stimulation of monocytes

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains

IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 50ul Nucleic Acid Extraction Mutations in this gene haveThis gene encodes the alpha chain of the interleukin 4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane bound protein, and this soluble form can inhibit IL4 mediated cell proliferation and IL5 upregulation by T