Rb Polyclonal Antibody, 50ul[BT-AP07690] Nucleic Acid Extraction MAPKKK5 contains 1|374 amino acids

MAPKKK5 contains 1|374 amino acids with all 11 kinase subdomains

developmental stage:Expressed in all fetal tissues examined

Two forms of tryptophanyl-tRNA synthetase exist

the protein was only detected in CD34+ progenitor cells present in blood and in CD31+ endothelial cells surrounding the blood vessels

|subunit:Mammalian complex I is composed of 45 different subunits

Rb Polyclonal Antibody, 50ul[BT-AP07690] Nucleic Acid Extraction MAPKKK5 contains 1|374 amino acidsThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.