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FCG3B Polyclonal Antibody, 100ul Immune Repertoire Sequencing The encoded protein can function

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FCG3B Polyclonal Antibody, 100ul Immune Repertoire Sequencing The encoded protein can functionThe protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly similar gene encoding a related protein is also found on chromosome 1.

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Description

The encoded protein can function as an elastase over a broad pH range in alveolar macrophages

Required for normal progression through the cell cycle

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain

Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene

and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7)

FCG3B Polyclonal Antibody, 100ul Immune Repertoire Sequencing The encoded protein can functionThe protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly similar gene encoding a related protein is also found on chromosome 1.

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